Dr. Shafqat Hussain

DS

Designation:

Phone:

Email: shafqat.hussain@kiu.edu.pk

Status:

Qualification

  • Ph.D. (Organic Chemistry) H. E. J. Research Institute for Chemistry, I.C.C.B.S., University of Karachi,
  • M.Sc. (Organic Chemistry) Federal Urdu University of Science and Technology, Karachi
  • B.Sc. (Chemistry) University of Karachi
  • F.Sc.(Pre-Medical) BIEK, Karachi
  • SSC FBISE, Islamabad

Experience

  • Junior Research Fellow, HEJ Research Institute of chemistry, ICCBS, university of Karachi, 2008-05-02, 2014-05 HEJ Research Institute of chemistry, ICCBS, university of Karachi
  • Assistant Professor, Karakoram International University, Gilgit, 2015-05-20, continue Karakoram International University, Gilgit

Awards

  • Assistant Professorship, Interim-Placement of Fresh PhD Program by Higher Education Commission of Pakistan
  • Junior Research Fellowship at HEJ Research Institute of Chemistry, ICCBS, University of Karachi, Pakistan.

Research Interests

  • Synthesis of structurally interesting and biologically relevant heterocyclic compounds
  • Discovery and the development of new reactions for organic synthesis
  • Designing and discovering novel compounds as potential drugs.

Publications

  • Oxadiazoles and Thiadiazoles: Novel α-Glucosidase Inhibitors, 1. Hamdy Kashtoh, Shafqat Hussain, Ajmal Khan, Syed Muhammad Saad, Jalaluddin A. J. Khan, Khalid Mohammed Khan, Shahnaz Perveen, M. Iqbal Choudhary. Oxadiazoles and Thiadiazoles: Novel α-Glucosidase Inhibitors, Bioorganic and Medicinal Chemistry, 22, 2014, 5454-5465.
  • Sodium Bromate/Sodium Hydrogen Sulfite: A New Catalyst for the Synthesis of Quinoxaline Derivatives, Khalid M. Khan, Shafqat Hussain, Shahanaz Perveen, Fazal Rahim, Sammer Yousuf and Ejaz Hussain, Sodium Bromate/Sodium Hydrogen Sulfite: A New Catalyst for the Synthesis of Quinoxaline Derivatives, Letters in Organic Chemistry, 2014, 426-431.
  • β-glucuronidase Inhibitory Studies on Coumarin Derivatives, Khalid Mohammed Khan, Muhammad Imran Fakhri, Nimra Naveed Shaikh, Syed Muhammad Saad, Shafqat Hussain, Shahnaz Perveen and Muhammad Iqbal Choudhary. β-glucuronidase Inhibitory Studies on Coumarin Derivatives, Medicinal Chemistry, 2014, 10, 778-782.
  • Evaluation of bisindole as potent β-glucuronidase inhibitors: Synthesis and in silico based studies., Khalid Mohammed Khan, Fazal Rahim, Abdul Wadood, Muhammad Taha, Momin Khan, Shagufta Naureen, Nida Ambreen, Shafqat Hussain, Shahnaz Perveen, Mohammad Iqbal Choudhary. Evaluation of bisindole as potent β-glucuronidase inhibitors: Synthesis and in silico based studies. Bioorganic and Medicinal Chemistry Letters, 2014, 24, 1825-1829.
  • Benzothiazole Derivatives: Novel Inhibitors of Methylglyoxal Mediated Glycation of Proteins In Vitro, Sanaullah Abbasi, Salma Mirza, Saima Rasheed, Shafqat Hussain, Jalaluddin A. J. Khan, Khalid Mohammed Khan, Shahnaz Perveen, M. Iqbal Choudhary. Benzothiazole Derivatives: Novel Inhibitors of Methylglyoxal Mediated Glycation of Proteins In Vitro, Medicinal Chemistry, 2014, 10, 824-835
  • Antiglycation Activity of Quinoline Derivatives- A New Therapeutic Class for the Management of Type 2 Diabetes, Bilquees Bano, Sanaullah Abbasi, Saima Rasheed, Shafqat Hussain, Jalaluddin A. J. Khan, Khalid Mohammed Khan and M. Iqbal Choudhary. Antiglycation Activity of Quinoline Derivatives- A New Therapeutic Class for the Management of Type 2 Diabetes. Medicinal Chemistry, 2014, 11, 60-68
  • Synthesis, Antimicrobial and Phytotoxic Activity of Amide Derivatives of L-( )-2,3- Diacetoxy-4-methoxy-4-oxo-butanoic acid, Mahrukh Malik, Sher Wali Khan, Javed Hussain Zaidi, Khalid Mohammed Khan, Shafqat Hussain, Shahnaz Perveen and Ghulam Abbas Miana. Synthesis, Antimicrobial and Phytotoxic Activity of Amide Derivatives of L-( )-2,3- Diacetoxy-4-methoxy-4-oxo-butanoic acid. Journal of Chemical Society Pakistan, 36, 2014, 170-176.
  • structure of methyl 2-(7-hydroxy-2-oxo-2H-chromen-4-yl)acetate, Sammer Yousuf, Shafqat Hussain, Khalid Mohammed Khan, Muhammad Shabeer and Shahnaz Perveen. Crystal structure of methyl 2-(7-hydroxy-2-oxo-2H- chromen-4-yl)acetate, Crystalography E. 2015, 71, 0677–0678.
  • Triazinoindole analogs as .potent inhibitors of α-glucosidase: Synthesis, biological evaluation and molecular docking studies, Fazal Rahim, Khadim Ullah, Hayat Ullah, Abdul Wadood, Muhammad Taha, Ashfaq Ur Rehman, Imad uddin, Muhammad Ashraf, Ayesha Shaukat, Wajid Rehman, Shafqat Hussain, Khalid Mohammed Khan. Triazinoindole analogs as .potent inhibitors of α-glucosidase: Synthesis, biological evaluation and molecular docking studies. Bioorganic Chemistry, 58, 2015, 81–87.
  • Synthesis, in vitro evaluation and molecular docking studies of thiazole derivatives as new inhibitors of α-glucosidase, Fazal Rahim , Hayat Ullah, Muhammad Tariq Javid, Abdul Wadood, Muhammad Taha, Muhammad Ashraf, Ayesha Shaukat, Muhammad Junaid, Shafqat Hussain, Wajid Rehman, Rashad Mehmood, Muhammad Sajid, Muhammad Naseem Khan and Khalid Mohammed Khan. Synthesis, in vitro evaluation and molecular docking studies of thiazole derivatives as new inhibitors of α-glucosidase Bioorganic Chemistry, 62, 2015, 15–21
  • Synthesis and Structure-activity Relationship of Thiobarbituric Acid Derivatives as Potent Inhibitors of Urease, Khalid Mohammed Khan, Fazal Rahim, Ajmal Khan, Muhammad Shabeer, Shafqat Hussain, Wajid Rehman, Muhammad Taha, Momin Khan, Shahnaz Perveen, and M. Iqbal Choudhary. Synthesis and Structure-activity Relationship of Thiobarbituric Acid Derivatives as Potent Inhibitors of Urease, Bioorganic & Medicinal Chemistry, 22 2014, 4119–4123
  • Synthesis and β-glucuronidase inhibitory activity of 2-arylquinazolin-4(3H)-ones, Khalid Mohammed Khan , Syed Muhammad Saad, Nimra Naveed Shaikh, Shafqat Hussain, Muhammad Imran Fakhri, Shahnaz Parveen, Muhammad Taha and Muhammad Iqbal Choudhary. Synthesis and β-glucuronidase inhibitory activity of 2-arylquinazolin- 4(3H)-ones, Bioorganic & Medicinal Chemistry, 22, 2014, 3449-3454.
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