Dr. Iftikhar Ali

Dr. Iftikhar Ali

Designation: Assistant Professor

Phone: 03339665739

Email: iftikhar.ali@kiu.edu.pk

Status: iftikhar.ali@kiu.edu.pk

Qualification

  • (2012) PhD (Dr. rer. nat.) University of Rostock
  • (2004) Bachelor Kohat University of Science and Technology
  • (2002) Intermediate Board of Intermediate and Secondary Education Kohat
  • (2000) Metric Board of Intermediate and Secondary Education Peshawar
  • (2006) M.Sc. Kohat University of Science and Technology Kohat

Experience

  • Junior Research Fellow HEJ Research Institute of Chemistry, University of Karachi
  • Assistant Professor Department of Chemistry, Karakoram International University
  • Guest Scientist University of Rostock

Projects

  • (2015 awarded by NRPU-HEC) Phytochemical Investigation and Bioassay Studies on the Ethnomedicinal Plants from Shigar valley, Skardu, Gilgit-Baltistan (Amounting to approx. PKR 5 Million)
  • (2013 awarded by SEED) Proximate Phytochemical Investigation on Plants from CKNP Region Used in Farmer’s Indigenous Treatment Practices for the Cure of Livestock Diseases in Gilgit-Baltistan (Amounting to PKR 1.0 Million)
  • (2012 awarded by SRG-HEC) Phytochemical Investigation and Biological Screening of Some Selected Ethno-Medicinal Plants From Gilgit-Baltistan (Amounting to PKR 0.5 Million)

Awards

  • 2013 Assistant Professorship on TTS by Higher Education Commission of Pakistan

  • 2010 PhD Fellowship, University of Rostock, Germany

  • 2009 IRSIP Fellowship by Higher Education Commission of Pakistan

  • 2012 Assistant Professorship on IPFP by Higher Education Commission of Pakistan

  • 2007 Junior Research Fellowship by HEJ Research Institute of Chemistry, ICCBS, University of Karachi, Pakistan

  • 2006 Gold Medal by Kohat University of Science and Technology, Pakistan

  • 2018 Best University Teacher Award (by HEC Pakistan)

Research Interests

  • Organic Synthesis
  • Phytochemical investigation

Publications

  • Significance of Bitter Leaf (Vernonia Amagdalina) In Tropical Diseases and Beyond: A Review., Egharevba, C., Osayemwenre, E., Imieje, V., Ahomafor, J., Akunyuli, C., Udu-Cosi, A. A., Theophilus, O., James, O., Ali, I., Falodun, A. (2014): Significance of Bitter Leaf (Vernonia Amagdalina) In Tropical Diseases and Beyond: A Review. Malaria Chemotherapy Control
  • Antimicrobial activity of two mellein derivatives isolated from an endophytic fungus., Hussain, H., Jabeen, F., Krohn, K., Al-Harrasi, A., Ahmad, M., Mabood, F., Shah, A., Badshah, A., Rehman, N. U., Green, I. R., Ali, I., Draeger, S., Schulz, B. (2014): Antimicrobial activity of two mellein derivatives isolated from an endophytic fungus. Medicinal Chemistry Research DOI 10.1007/s00044-014-1250-3.
  • Isolation of Diterpenoids from Jatropha podagrica against Hepatitis C virus., Falodun, A., Imieje V., Erharuyi, O., Joy-Ahomafora, J., Akunyuli, C., Udu-Cosi, A. A., Theophilus, O., Ali, I., Albadry, M., Fasinu, P., Hamann, M. T. (2014): Isolation of Diterpenoids from Jatropha podagrica against Hepatitis C virus. Journal of African Association of Physiological Sciences 2:1, 21-25.
  • Characterization and Antimicrobial Evaluation of Epiafzelechin from the Stem Bark of Calliandra surinamensis Benth. , Ali, I., Faodun, A., Josephs, G. C., Hussain, H., Karsten, U., Langer, P. (2013): Characterization and Antimicrobial Evaluation of Epiafzelechin from the Stem Bark of Calliandra surinamensis Benth. African Journal of Pharmaceutical Research and Development 5:1, 25-29.
  • A review of breast cancer and role of phytooestrogens as anticancer agents. , Falodun, A., Engel-Lutz, N., Falodun, J. E., Ali, I., Opperman, C., Erharuyi, O., Imiejo, V. O., Kragl, U., Nebe, B., Langer, P. (2013): A review of breast cancer and role of phytooestrogens as anticancer agents. University of Benin Journal of Science and Technology 2:1, 75-84.
  • Synthesis of Trifluoromethyl-substituted di- and Terphenyls by Siteselective Suzuki-Miyaura Reactions of Various Dihalogenated Trifluoromethyl-benzene Derivatives., Ali, I., Siyo, B., Hassan, Z., Malik, I., Ullah, I., Ali, A., Nawaz, M., Iqbal, J., Villinger, A., Langer, P. (2013): Synthesis of Trifluoromethyl-substituted di- and Terphenyls by Siteselective Suzuki-Miyaura Reactions of Various Dihalogenated Trifluoromethyl-benzene Derivatives. Journal of Fluorine Chemistry 145, 18-34.
  • Synthesis of Tetraaryl-p-benzoquinones and 2,3-diaryl-1,4-naphthoquinones via Suzuki–Miyaura Cross-coupling Reactions. , Hassan, Z., Ullah, I., Ali, I., Khera, R. A., Knepper, I., Ali, A., Patonay, T., Villinger, A., Langer, P. (2013): Synthesis of Tetraaryl-p-benzoquinones and 2,3-diaryl-1,4-naphthoquinones via Suzuki–Miyaura Cross-coupling Reactions. Tetrahedron 69:2, 460-469.
  • Isolation of Trimethylammoniumyl–Acetate Monohydrate from Cola Lepidota Seeds: Antiproliferative Activity of Extracts and Fractions., Falodun, A., Engel-Lutz, N., Oppermann, C., Ali, I., Villinger, A., Kragl, U., Nebe, B., Langer, P. (2013): Isolation of Trimethylammoniumyl–Acetate Monohydrate from Cola Lepidota Seeds: Antiproliferative Activity of Extracts and Fractions. Journal of Herbs, Spices
  • The Genus Pluchea: Phytochemistry, Traditional Uses, and Biological Activities., Hussain, H., Al-Harrasi, A., Abbas, G., Rehman, N., Mabood, F., Ahmed, I., Saleem, M., Ree, T. V., Green, I. R., Anwar, A., Badshah, A., Shah, A., Ali, I. (2013): The Genus Pluchea: Phytochemistry, Traditional Uses, and Biological Activities. Chemistry
  • Regioselective Palladium(0)-Catalysed Cross-coupling Reactions of 5,7-dichloro-1,6-naphthyridine. , Ali, I., Hassan, Z., Hein, M., Falodun, A., Patonay, T., Villinger, A., Langer, P. (2012): Regioselective Palladium(0)-Catalysed Cross-coupling Reactions of 5,7-dichloro-1,6-naphthyridine. Synthesis 44:14, 2255-2263.
  • Regioselective Palladium(0)-Catalysed Cross-coupling Reactions of 2,6-dichloroquinoxaline., Ali, I., Siyo, B., Al-Soud, Y., Villinger, A., Langer, P. (2012): Regioselective Palladium(0)-Catalysed Cross-coupling Reactions of 2,6-dichloroquinoxaline. Synthesis 44:11, 1637-1646.
  • Transition-Metal-Catalyzed Arylation of 1-Deazapurines via C–H Bond Activation. , Iaroshenko, V. O., Ali, I., Mkrtchyan, S., Semeniuchenko, V., Ostrovskyi, D., Langer, P. (2012): Transition-Metal-Catalyzed Arylation of 1-Deazapurines via C–H Bond Activation. Synlett 23:18, 2603-2608.
  • Nepetadiol – A New Triterpenediol from Nepeta suavis. , Khan, F. U., Hussain, J., Khan, I. U., Ullah, R., Ali, I., Muhammad, Z., Hussain, H., Shah, M. R. (2011): Nepetadiol – A New Triterpenediol from Nepeta suavis. Chemistry of Natural Compounds 47:2, 234-236.
  • Two New Antioxidant Bergenin Derivatives from the Stem of Rivea hypocrateriformis., Zamarrud., Ali, I., Hussain, H., Ahmad, V. U., Qaiser, M., Amyn, A., Mohammad, F. V. (2011): Two New Antioxidant Bergenin Derivatives from the Stem of Rivea hypocrateriformis. Fitoterapia 82, 722-725.
  • Synthesis and Photophysical Properties of Alkynylated Pyrimidines by Site-selective Sonogashira Reactions of 2,4,5,6-tetrachloropyrimidine, First Synthesis of Tetraalkynyl1-pyrimidines. , Malik, I., Ahmed, Z., Reimann, S., Ali I., Villinger A., Langer, P. (2011): Synthesis and Photophysical Properties of Alkynylated Pyrimidines by Site-selective Sonogashira Reactions of 2,4,5,6-tetrachloropyrimidine, First Synthesis of Tetraalkynyl1-pyrimidines. European Journal of Organic Chemistry 11, 2088-2093.
  • An Efficient Synthesis of 6-nitro- and 6-amino-3Himidazo[4,5-b]pyridines by Cyclocondensation of 1-substituted 1H-imidazol-5-amines with 3-nitro-4H-chromen-4-one., Ostrovskyi, D., Iaroshenko, V. O., Petrosyan, A., Dudkin, S., Ali, I., Villinger, A., Tolmachev, A., Langer, P. (2010): An Efficient Synthesis of 6-nitro- and 6-amino-3Himidazo[4,5-b]pyridines by Cyclocondensation of 1-substituted 1H-imidazol-5-amines with 3-nitro-4H-chromen-4-one. Synlett 15, 2299-2303.
  • 3-methoxalylchromone – A Versatile Reagent for the Regioselective Synthesis of 1-desazapurine., Ostrovskyi, D., Iaroshenko, V. O., Ali, I., Mkrtchyan, S., Villinger, A., Tolmachev, A., Langer, P. (2010): 3-methoxalylchromone – A Versatile Reagent for the Regioselective Synthesis of 1-desazapurine. Synthesis 1, 133-141.
  • Biological activities of Suaeda heterophylla and Bergenia stracheyi, Ali, I.; Bibi, S.; Hussain, H.; Bano, F.; Ali, S.; Khan, S. W.; Ahmad, V. U. Biological activities of Suaeda heterophylla and Bergenia stracheyi. Asian Pac. J. Trop. Dis. 2014; 4(Suppl 2): S885-S889.
  • Microdiplanol and Microdiplane: A new m-anisaldehyde and a new 24-methylcholestanol derivative from the Endophytic Fungus Microdiplodia sp. , Microdiplanol and Microdiplane: A new m-anisaldehyde and a new 24-methylcholestanol derivative from the Endophytic Fungus Microdiplodia sp. H. Hussain, K. Krohn, A. Al-Harrasi, S. F. Kouam, G. Abbas, M. A. Raees, T. Dzeha, R. Ullah, A. Zahoor, A. Shahf A. Badshah, A. Khan, I. Ali, B. Schulz. Journal Asian Natural Product Research 2015 (DOI:10.1080/10286020.2014.989221).
  • Pharmacological assessment of hispidulin - a natural bioactive flavone., Muhammad Atif, Iftikhar Ali, Ajaz Hussain, Syed Viqar Hyder, Basit Niaz, Farhan Ahmed Khan, Aneela Maalik, Umar Farooq. Pharmacological assessment of hispidulin - a natural bioactive flavone. Acta Poloniae Pharmaceutica - Drug Research 72, 5, 829-842, 2015.
  • Pharmacology and synthesis of daurichromenic acid as a potent anti-HIV agent, Bukhari, S. M.; Ali, I.; Zaidi, A.; Iqbal, N.; Noor, T.; Mehmood, R.; Chisti, M. S.; Niaz, B.; Rashid, U.; Atif, M. Pharmacology and synthesis of daurichromenic acid as a potent anti-HIV agent. Acta Poloniae Pharmaceutica - Drug Research 2015, 72, 6, 1059-1071.
  • Antitumor evaluation of two selected Pakistani plant extracts on human bone and breast cancer cell lines, Engel N, Iftikhar Ali, Adamus A, Frank M, Akber Dad, Ali S, Nebe B, Atif M, Ismail M, Langer P, Ahmad VU. Antitumor evaluation of two selected Pakistani plant extracts on human bone and breast cancer cell lines. BMC Complementary and Alternative Medicine 2016, 16:244.
  • Comparative Enzyme Inhibition Study of 1-Deazapurines, Iftikhar Ali, Ajmal Khan, Amjad Hussain, Umar Farooq, Muhammad Ismail, Viqar Hyder, Viqar U. Ahmad, Viktor O. Iaroshenko, Hidayat Hussain, Peter Langer. Comparative Enzyme Inhibition Study of 1-Deazapurines. Med. Chem. Res. 2016. DOI: 10.1007/s00044-016-1700-1
  • Ursolic acid derivatives for pharmaceutical use: a patent review (2012-2016), Hussain H, Green IR, Iftikhar Ali, Khan IA, Ali Z, Al-Sadi AM, Ahmed I. Ursolic acid derivatives for pharmaceutical use: a patent review (2012-2016). Expert Opin Ther Pat. 2017 Jun 30:1-12.
  • DOCUMENTATION OF ETHNOVETERINARY PRACTICES IN THE CKNP REGION, GILGIT-BALTISTAN, Iftikhar Ali, Hidayat Hussain, Huma Batool, Akber Dad, Ghulam Raza, Abiodun Falodun, Raza Ullah, Viqar Uddin Ahmad. DOCUMENTATION OF ETHNOVETERINARY PRACTICES IN THE CKNP REGION, GILGIT-BALTISTAN. Int. J. Phytomed. 2017, 9, 2.
  • THE PHYTOCHEMICAL INVESTIGATION AND BIOLOGICAL ACTIVITIES OF BERBERIS ORTHOBOTRYS, Akber Dad, Iftikhar Ali, Nadja Engel, Muhammad Atif, Hidayat Hussain, Viqar Uddin Ahmad, Peter Langer, Ivan R. Green. THE PHYTOCHEMICAL INVESTIGATION AND BIOLOGICAL ACTIVITIES OF BERBERIS ORTHOBOTRYS. Int. J. Phytomed. 2017, 9, 2.
  • Qualitative Analysis for Phytochemicals of Selected Medicinal Plants from Gilgit-Baltistan, Pakistan, Muhammad Ismail, Noor-ul-Haq, Sajjad Ali, Iftikhar Ali, Rubina Shaheen, Ghulam Murtaza, Abdurrazaq. Qualitative Analysis for Phytochemicals of Selected Medicinal Plants from Gilgit-Baltistan, Pakistan. Asian J. Chem. 2017, 29(9), 1929-1932.
  • Screening of Some Medicinal Plants for Antibacterial Activity against Conjunctivitis, Meher S, Ali I, Sami A, Naheed N, Khan SA, Ismail M. Screening of Some Medicinal Plants for Antibacterial Activity against Conjunctivitis. The JAPS 2017, 27(6).
  • GC-MS Analysis of Bioactive Compounds in Fractions of Corydalis adiantifolia., Ali Iftikhar, Khan SS, Khan A, Ali Z, Bhatti HA, Bankeu JJK, and Ahmad VU. GC-MS Analysis of Bioactive Compounds in Fractions of Corydalis adiantifolia. Tropical Journal of Natural Product Research 2018, 2(6), 282-289.
  • Pobeguinine: a monoterpene indole alkaloid and other bioactive constituents from the stem bark of Nauclea pobeguinii, Bankeu JJK, Madjouka S, Feuya GRT, Fongang YSF, Siddiqui S, Ali I, Mehreen L, Lenta BN, Yousuf S, Noungoué DT, Ngouela AS, Ali MS. Pobeguinine: a monoterpene indole alkaloid and other bioactive constituents from the stem bark of Nauclea pobeguinii. Z. Naturforsch. 2018, doi: 10.1515/znc-2017-0127
  • Bioactive chromone constituents from Vitex negundo alleviate pain and inflammation, Khan A, Naz S, Farooq U, Shahid M, Ullah I, Ali I. Bioactive chromone constituents from Vitex negundo alleviate pain and inflammation" Journal of Pain Research 2018, 11, 95-102
  • Berberis orthobotrys – A promising herbal anti-tumorigenic candidate for the treatment of pediatric alveolar rhabdomyosarcoma, Adamus A, Peer K, Ali I, Lisec J, Falodun A, Frank M, Seitz G, Engel N. Berberis orthobotrys – A promising herbal anti-tumorigenic candidate for the treatment of pediatric alveolar rhabdomyosarcoma. Journal of Ethnopharmacology 2018 (doi: 10.1016/j.jep.2018.10.002)
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