Dr. Iftikhar Ali

Dr. Iftikhar Ali

Designation: Associate Professor (Tenured)

Phone: +923339665739

Email: iftikhar.ali@kiu.edu.pk

Status: Regular Faculty

  • (2012) PhD (Dr. rer. nat.) University of Rostock
  • (2004) Bachelor Kohat University of Science and Technology
  • (2002) Intermediate Board of Intermediate and Secondary Education Kohat
  • (2000) Metric Board of Intermediate and Secondary Education Peshawar
  • (2006) M.Sc. Kohat University of Science and Technology Kohat
  • (2021) PostDoc Shandong Analysis and Test Center
  • Junior Research Fellow HEJ Research Institute of Chemistry, University of Karachi
  • Assistant Professor Department of Chemistry, Karakoram International University
  • Guest Scientist University of Rostock
  • Guest Professor Shandong Normal University
  • (2015 awarded by NRPU-HEC) Phytochemical Investigation and Bioassay Studies on the Ethnomedicinal Plants from Shigar valley, Skardu, Gilgit-Baltistan (Amounting to approx. PKR 5 Million)
  • (2013 awarded by SEED) Proximate Phytochemical Investigation on Plants from CKNP Region Used in Farmer’s Indigenous Treatment Practices for the Cure of Livestock Diseases in Gilgit-Baltistan (Amounting to PKR 1.0 Million)
  • (2012 awarded by SRG-HEC) Phytochemical Investigation and Biological Screening of Some Selected Ethno-Medicinal Plants From Gilgit-Baltistan (Amounting to PKR 0.5 Million)

  • 2013 Assistant Professorship on TTS by Higher Education Commission of Pakistan

  • 2010 PhD Fellowship, University of Rostock, Germany

  • 2009 IRSIP Fellowship by Higher Education Commission of Pakistan

  • 2012 Assistant Professorship on IPFP by Higher Education Commission of Pakistan

  • 2007 Junior Research Fellowship by HEJ Research Institute of Chemistry, ICCBS, University of Karachi, Pakistan

  • 2006 Gold Medal by Kohat University of Science and Technology, Pakistan

  • 2018 Best University Teacher Award (by HEC Pakistan)

  • 2019 Associate Professorship (Tenured)

  • Organic Synthesis
  • Phytochemical investigation

  • High-speed counter-current chromatography

    • Significance of Bitter Leaf (Vernonia Amagdalina) In Tropical Diseases and Beyond: A Review., Egharevba, C., Osayemwenre, E., Imieje, V., Ahomafor, J., Akunyuli, C., Udu-Cosi, A. A., Theophilus, O., James, O., Ali, I., Falodun, A. (2014): Malaria Chemotherapy Control
    • Antimicrobial activity of two mellein derivatives isolated from an endophytic fungus., Hussain, H., Jabeen, F., Krohn, K., Al-Harrasi, A., Ahmad, M., Mabood, F., Shah, A., Badshah, A., Rehman, N. U., Green, I. R., Ali, I., Draeger, S., Schulz, B. (2014): Medicinal Chemistry Research DOI 10.1007/s00044-014-1250-3.
    • Isolation of Diterpenoids from Jatropha podagrica against Hepatitis C virus., Falodun, A., Imieje V., Erharuyi, O., Joy-Ahomafora, J., Akunyuli, C., Udu-Cosi, A. A.,Theophilus, O., Ali, I., Albadry, M., Fasinu, P., Hamann, M. T. (2014): Journal of African Association of Physiological Sciences 2:1, 21-25.
    • Characterization and Antimicrobial Evaluation of Epiafzelechin from the Stem Bark of Calliandra surinamensis Benth. , Ali, I., Faodun, A., Josephs, G. C., Hussain, H., Karsten, U., Langer, P. (2013): African Journal of Pharmaceutical Research and Development 5:1, 25-29.
    • A review of breast cancer and role of phytooestrogens as anticancer agents. , Falodun, A., Engel-Lutz, N., Falodun, J. E., Ali, I., Opperman, C., Erharuyi, O., Imiejo, V. O., Kragl, U., Nebe, B., Langer, P. (2013): University of Benin Journal of Science and Technology 2:1, 75-84.
    • Synthesis of Trifluoromethyl-substituted di- and Terphenyls by Siteselective Suzuki-Miyaura Reactions of Various Dihalogenated Trifluoromethyl-benzene Derivatives., Ali, I., Siyo, B., Hassan, Z., Malik, I., Ullah, I., Ali, A., Nawaz, M., Iqbal, J., Villinger, A., Langer, P. (2013): Journal of Fluorine Chemistry 145, 18-34.
    • Synthesis of Tetraaryl-p-benzoquinones and 2,3-diaryl-1,4-naphthoquinones via Suzuki–Miyaura Cross-coupling Reactions. , Hassan, Z., Ullah, I., Ali, I., Khera, R. A., Knepper, I., Ali, A., Patonay, T., Villinger, A., Langer, P. (2013): Tetrahedron 69:2, 460-469.
    • Isolation of Trimethylammoniumyl–Acetate Monohydrate from Cola Lepidota Seeds: Antiproliferative Activity of Extracts and Fractions., Falodun, A., Engel-Lutz, N., Oppermann, C., Ali, I., Villinger, A., Kragl, U., Nebe, B., Langer, P. (2013): Journal of Herbs, Spices
    • The Genus Pluchea: Phytochemistry, Traditional Uses, and Biological Activities., Hussain, H., Al-Harrasi, A., Abbas, G., Rehman, N., Mabood, F., Ahmed, I., Saleem, M., Ree, T. V., Green, I. R., Anwar, A., Badshah, A., Shah, A., Ali, I. Chemistry & Biodiversity 2013, 10, 11, 1944-71.
    • Regioselective Palladium(0)-Catalysed Cross-coupling Reactions of 5,7-dichloro-1,6-naphthyridine. , Ali, I., Hassan, Z., Hein, M., Falodun, A., Patonay, T., Villinger, A., Langer, P. (2012): Synthesis 44:14, 2255-2263.
    • Regioselective Palladium(0)-Catalysed Cross-coupling Reactions of 2,6-dichloroquinoxaline., Ali, I., Siyo, B., Al-Soud, Y., Villinger, A., Langer, P. (2012): Synthesis 44:11, 1637-1646.
    • Transition-Metal-Catalyzed Arylation of 1-Deazapurines via C-H Bond Activation. , Iaroshenko, V. O., Ali, I., Mkrtchyan, S., Semeniuchenko, V., Ostrovskyi, D., Langer, P. (2012): Synlett 23:18, 2603-2608.
    • Nepetadiol: A New Triterpenediol from Nepeta suavis. , Khan, F. U., Hussain, J., Khan, I. U., Ullah, R., Ali, I., Muhammad, Z., Hussain, H., Shah, M. R. (2011): Chemistry of Natural Compounds 47:2, 234-236.
    • Two New Antioxidant Bergenin Derivatives from the Stem of Rivea hypocrateriformis., Zamarrud., Ali, I., Hussain, H., Ahmad, V. U., Qaiser, M., Amyn, A., Mohammad, F. V. (2011): Fitoterapia 82, 722-725.
    • Synthesis and Photophysical Properties of Alkynylated Pyrimidines by Site-selective Sonogashira Reactions of 2,4,5,6-tetrachloropyrimidine, First Synthesis of Tetraalkynyl1-pyrimidines. , Malik, I., Ahmed, Z., Reimann, S., Ali I., Villinger A., Langer, P. (2011): European Journal of Organic Chemistry 11, 2088-2093.
    • An Efficient Synthesis of 6-nitro- and 6-amino-3Himidazo[4,5-b]pyridines by Cyclocondensation of 1-substituted 1H-imidazol-5-amines with 3-nitro-4H-chromen-4-one., Ostrovskyi, D., Iaroshenko, V. O., Petrosyan, A., Dudkin, S., Ali, I., Villinger, A., Tolmachev, A., Langer, P. (2010): Synlett 15, 2299-2303.
    • 3-methoxalylchromone: A Versatile Reagent for the Regioselective Synthesis of 1-desazapurine., Ostrovskyi, D., Iaroshenko, V. O., Ali, I., Mkrtchyan, S., Villinger, A., Tolmachev, A., Langer, P. (2010): Synthesis 1, 133-141.
    • Biological activities of Suaeda heterophylla and Bergenia stracheyi, Ali, I.; Bibi, S.; Hussain, H.; Bano, F.; Ali, S.; Khan, S. W.; Ahmad, V. U. Asian Pac. J. Trop. Dis. 2014; 4(Suppl 2): S885-S889.
    • Microdiplanol and Microdiplane: A new m-anisaldehyde and a new 24-methylcholestanol derivative from the Endophytic Fungus Microdiplodia sp. , H. Hussain, K. Krohn, A. Al-Harrasi, S. F. Kouam, G. Abbas, M. A. Raees, T. Dzeha, R. Ullah, A. Zahoor, A. Shahf A. Badshah, A. Khan, I. Ali, B. Schulz. Journal Asian Natural Product Research 2015 (DOI:10.1080/10286020.2014.989221).
    • Pharmacological assessment of hispidulin - a natural bioactive flavone., Muhammad Atif, Iftikhar Ali, Ajaz Hussain, Syed Viqar Hyder, Basit Niaz, Farhan Ahmed Khan, Aneela Maalik, Umar Farooq. Acta Poloniae Pharmaceutica - Drug Research 72, 5, 829-842, 2015.
    • Pharmacology and synthesis of daurichromenic acid as a potent anti-HIV agent, Bukhari, S. M.; Ali, I.; Zaidi, A.; Iqbal, N.; Noor, T.; Mehmood, R.; Chisti, M. S.; Niaz, B.; Rashid, U.; Atif, M. Acta Poloniae Pharmaceutica - Drug Research 2015, 72, 6, 1059-1071.
    • Antitumor evaluation of two selected Pakistani plant extracts on human bone and breast cancer cell lines, Engel N, Iftikhar Ali, Adamus A, Frank M, Akber Dad, Ali S, Nebe B, Atif M, Ismail M, Langer P, Ahmad VU. BMC Complementary and Alternative Medicine 2016, 16:244.
    • Comparative Enzyme Inhibition Study of 1-Deazapurines, Iftikhar Ali, Ajmal Khan, Amjad Hussain, Umar Farooq, Muhammad Ismail, Viqar Hyder, Viqar U. Ahmad, Viktor O. Iaroshenko, Hidayat Hussain, Peter Langer. Med. Chem. Res. 2016. DOI: 10.1007/s00044-016-1700-1
    • Ursolic acid derivatives for pharmaceutical use: a patent review (2012-2016), Hussain H, Green IR, Iftikhar Ali, Khan IA, Ali Z, Al-Sadi AM, Ahmed I. Expert Opin Ther Pat. 2017 Jun 30:1-12.
    • Documentation of Ethnoveterinary practices in the CKNP region, Gilgit-Baltistan, Iftikhar Ali, Hidayat Hussain, Huma Batool, Akber Dad, Ghulam Raza, Abiodun Falodun, Raza Ullah, Viqar Uddin Ahmad. Int. J. Phytomed. 2017, 9, 2.
    • The phytochemical investigation and biological activities of Berberis orthobotrys, Akber Dad, Iftikhar Ali, Nadja Engel, Muhammad Atif, Hidayat Hussain, Viqar Uddin Ahmad, Peter Langer, Ivan R. Green. Int. J. Phytomed. 2017, 9, 2.
    • Qualitative Analysis for Phytochemicals of Selected Medicinal Plants from Gilgit-Baltistan, Pakistan, Muhammad Ismail, Noor-ul-Haq, Sajjad Ali, Iftikhar Ali, Rubina Shaheen, Ghulam Murtaza, Abdurrazaq. Asian J. Chem. 2017, 29(9), 1929-1932.
    • Screening of Some Medicinal Plants for Antibacterial Activity against Conjunctivitis, Meher S, Ali I, Sami A, Naheed N, Khan SA, Ismail M. The JAPS 2017, 27(6).
    • GC-MS Analysis of Bioactive Compounds in Fractions of Corydalis adiantifolia., Ali Iftikhar, Khan SS, Khan A, Ali Z, Bhatti HA, Bankeu JJK, and Ahmad VU. Tropical Journal of Natural Product Research 2018, 2(6), 282-289.
    • Pobeguinine: a monoterpene indole alkaloid and other bioactive constituents from the stem bark of Nauclea pobeguinii, Bankeu JJK, Madjouka S, Feuya GRT, Fongang YSF, Siddiqui S, Ali I, Mehreen L, Lenta BN, Yousuf S, Noungoué DT, Ngouela AS, Ali MS. Z. Naturforsch. 2018, doi: 10.1515/znc-2017-0127
    • Bioactive chromone constituents from Vitex negundo alleviate pain and inflammation, Khan A, Naz S, Farooq U, Shahid M, Ullah I, Ali I. Journal of Pain Research 2018, 11, 95-102
    • Berberis orthobotrys – A promising herbal anti-tumorigenic candidate for the treatment of pediatric alveolar rhabdomyosarcoma, Adamus A, Peer K, Ali I, Lisec J, Falodun A, Frank M, Seitz G, Engel N. Journal of Ethnopharmacology 2018 (doi: 10.1016/j.jep.2018.10.002)
    • Protein tyrosine phosphatase 1B (PTP1B) inhibitors as potential anti-diabetes agents: patent review (2015-2018), Hussain H, Abbas G, Hussain W, Ali I. Expert Opinion on Therapeutic Patents 2019, 29(9), 689-702.
    • Dipeptidyl peptidase IV inhibitors as a potential target for diabetes: patent review (2015-2018), Hussain H, Abbas G, Green IR, Ali I. Expert Opinion on Therapeutic Patents 2019, 29(7), 535-553.
    • Nematicidal Properties of Some Medicinal Plants from Selected Flora of Gilgit-Baltistan, Ismail M, Fayyaz S, Azad M, Javed S, Ali I, Ali S, Hussain S. The JAPS 20119, 29(4) 1182-1187.
    • Phytochemical and Bioactivity Study of Corydalis adiantifolia: A Herbal Hair Tonic from Baltistan, Ali I, Ali Z, Alishba, Zamarrud, Hussain H, Ahmad VU. Journal of The Chemical Society of Pakistan 2019, 41, 3.
    • Isolation of Anemonin from Pulsatilla wallichiana and Biological Activities, Ali I, Khatoon S, Amber F, Abbas Q, Ismail M, Engel N. Journal of The Chemical Society of Pakistan 2019, 41, 2, 325-333.
    • Isolation of Phytochemical Constituents from Hunteria umbellata K. Schum, Ali I, Falodun A, Siyo B, Bankeu JJK, Hussain H, Langer P. Tropical Journal of Natural Product Research 2019, 3 (3), 95-98.
    • Berberis orthobotrys – A promising herbal anti-tumorigenic candidate for the treatment of pediatric alveolar rhabdomyosarcoma, Adamus A, Peer K, Ali I, Lisec J, Falodun A, Frank M, Seitz G, Engel N. Journal of Ethnopharmacology 2019 (doi: 10.1016/j.jep.2018.10.002).
    • A simple and efficient linear gradient coupled with inner-recycling high-speed counter-current chromatography mode for the preparative separation of flavonoid glycosides from leaves of custard apple, Song S, Li K, Cui L, Yu J, Ali I, Zhu a H, Wang Q, Wang X, Wang D. Journal of Chromatography A 2020, 1615 (2020) 460719.
    • Evaluation of nematocidal effects of some medicinal plant extracts against root-nnot nematodes (Meloidogyne incognita)., Ismail M, Fayyaz S, Kowsar A, Javed S, Ali I,1 Ali S, Hussain F, Ali H. Italian Journal of Agronomy 2020, 15:1475.
    • Isolation and Anticancer Activity of Hispidulin from Saussurea simpsoniana and Lupeol from Vincetoxicum arnottianum. , Hassan G, Zahra Q, Ali I, Engel N, Ali K, Bahreen G, Ahmad VU, Aziz S, Wang D. Trop. J. Nat. Prod. Res. 2020, 4(2):31-35.
    • Flavonoid epimers from custard apple leaves, a rapid screening and separation by HSCCC and their antioxidant and hypoglycaemic activities evaluation., Zhu H, Chen L, Yu J, Cui L, Ali I, Song X, Park JH, Wang D and Wang X. Scientific Reports 2020, (2020) 10:8819.
    • Quantum/carbon dots-based fluorescent assays for enzyme activity. , Tong X, Shi S, Tong C, Ali I, Long R, Zhu Y. Trends in Analytical Chemistry 2020, DOI: 10.1016/j.trac.2020.116008.
    • Benzyloxylonchocarpin and Muracatanes A-C from Ranunculus muricatus L. and their biological effects., Hussain H, Ali I, Wang D, Mamadalieva NZ, Hussain W, Csuk R, Loesche A, Fischer L, Staerk D, Anam S, AlZain MN, Mushtaq M, Ul-Haq Z, Ullah R, Noman OM, Abbas G, Green IR. Biomolecules 2020, 10, 1562.
    • Synthetic studies towards fungal glycosides: an overview., Hussain H, Ali I, Elizbit, Hussain W, Mamadalieva NZ, Hussain A, Ali M, Ahmed I, Ullah I, Green IR. Current Organic Chemistry 2020, 24, 1-37.
    • Ethnopharmacological survey of herbal remedies used in the treatment of hepatitis., Hussain W, Batool S, Bahar S, Shahida B, Bangash B, Ali A, Hussain H, Ali I, Ali M, Bussmann RW. Ethnobotany Research & Applications 2020, DOI: 10.32859/era.20.24.1-29.
    • Cichorins d-f: Three new compounds from Cichorium intybus and their biological effects., Khan MF, Nasr FA, Noman OM, Alyhya NA, Ali I, Saoud M, Rennert R, Dube M, Hussain W, Green IR, Omer Ahmed M. Basudan OAM, Riaz Ullah R, Shamsa Hilal Anazi SH, Hussain H. Molecules 2020, 25, 4160.
    • Efficient extraction and purification of benzo[c]phenanthridine alkaloids from Macleaya cordata (Willd) R. Br. by combination of ultrahigh pressure extraction and pH-zone-refining counter-current chromatography with anti-breast cancer activity in vitro., Ali I, Li J, Cui L, Zhao H, He Q, Wang D. Phytochemical Analysis 2020, 1–10, DOI: 10.1002/pca.2990.
    • Patent 1 [Method for mass separation of compounds from Bergenia and detection method for antioxidation], Wang D, Ali Iftikhar, Aziz S, Shi S, Li C, Guo Y, Gang L. Application No. CN202010876173.5, Appl. date: 2020.08.25, Pub date: 2020.10.23
    • Patent 2 [A screening and separation method for hypoglycemic functional compounds in plants], Wang D, Shi S, Li C, Lu C, Tommy, Ali Iftikhar, Aziz S, Rong S, Ping Y. L. Application No. 202010865223.X, Appl. date: 2020.08.25, Pub date: 2020.10.23;
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